Recombinant Human TPO (thrombopoietin) 10ug expressed in human cells

Description

Summer Promotion
Recombinant Human TPO
Product Specifications
Expression of Human Proteins in Human Cells
Extreme low Endotoxin
High Purity
Animal Free and Xeno Free
T
ag Free
Source:
Human cells derived
Structure:
Glycosylated monomer
Purity:
>95% by SDS-PAGE
Endotoxin Level:
<0.5EU/ug
Molecular Weight:
80-85kDa
Formulation:
L
yophilized from a 0.2μm filtered solution in PBS without carrier protein
Activity Assay
The activity was measured by its ability to stimulate the proliferation of human Mo7e cells.
Reconstitution
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Protein Description
Recombinant human thrombopoietin  expressed in engineered human cells. TPO belongs to the EPO/TPO protein family. TPO protein is an 80 to 85 kDa monomeric glycoprotein. TPO is primarily produced in the liver and regulates the formation of megakaryocytes and platelets. C terminal domain glycosylation is thought to be important for the secretion of TPO from cells and for survival of TPO in the circulation.
References
Kitamura, T, et al. (1989) J. Cell Physiol. 140, 323-334.
Kaushansky, K, (1998) NEJM 339, 746-754